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Farmaci in Gravidanza e Allattamento

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Farmaci antitossse e decongestionanti nasali: nessuna seria controindicazione per la somministrazione in gravidanza e allattamento in condizioni fisiologiche.

Benagol pastiglie: I principi attivi 2,4-diclorobenzil alcool e amilmetacresolo sono dotati di attività antibatterica locale ad ampio spettro su patogeni gram-positivi e gram-negativi, e su miceti presenti nel cavo orofaringeo. Il mentolo esplica una azione balsamica. L’acido ascorbico ha proprietà antiossidanti e capillaro-protettive. E’ un utile coadiuvante del trattamento delle malattie da raffreddamento. Pur essendo un prodotto “da banco” e quindi abitualmente e a torto dispensato senza obbligo di ricetta medica, deve essere somministrato solo in caso di effettiva necessità e sotto la responsabilità del medico o ginecologo curante.

Acetilcisteina: L’Acetilcisteina (Fluimucil, Solmucol; NAC, N-Acetilcisteina) è una sostanza ad azione mucolitica: riduce la viscosità del muco rompendo I ponti disulfuro delle glicoproteine. E’ utilizzata anche negli interventi di angioplastica per ridurre l’incidenza di nefropatia indotta dai mezzi di contrasto. E’ utilizzata inoltre per I casi di ipercoagulabilità seminale nei maschi e nei casi di scarsezza o ispessimento del muco cervicale nelle donne. Solumucol cpr 200 mg contiene aspartame, fonte di fenilalanina; è quindi controindicato in pazienti con fenilchetonuria. Inoltre l’aspartame è un farmaco dotato di notevole tossicità e quindi, avendo a disposizione numerosi farmaci alternative, è assolutamente controindicato in gravidanza e allattamento.

Tab. 37 – Antitosse e decongestionanti nasali

Management

antitosse

Codeina

Codipront, Hederix plan supp, gocce

Ctg D della FDA

teratogeni <14 w

malformazioni cardiache, malformazioni scheletriche,
malformazioni del tubo digerente

Sindrome da astinenza nel neonato

Diidrocodeina

Paracodina

Sedativi centrali

Destrometorfano (Bechilar, Lisomucil, Aricodil, Romilar)

Ctg A

espettoranti

Ambroxolo (Fluibron)

Ctg A2

Bromexina (Bisolvon, Taugliucolo)

mucolitici

Larsobrerolo

Sobrepin

Ctg B3

controindicazione in allattamento

Eccipienti: aspartame, sorbitolo e colorante E110

acetilcisteina

Acetilcisteina, Fluimucil, Mucisol, Mucomucil, Viks
tosse

Ctg A2

Solmucol

B3

contiene aspartame

decongestionanti nasali

Efedrina (ß-mimetico)

Traminic flu,
Isonefrine, Argotone, Deltarinolo, Rinovit,

Linfovir spray nasale (resveratrolo)

Tonimer soft spray nasale

Ctg A3 della
FDA

Ctg A

Pseudoefedrina

Rondec

Fenilpropanolamina

Triaminic,
temporinolo

Nafazolina (ß-mimetico)

Collirio alfa, Imdazyl collirio

cortisonici

Beclometasone

Becotide

B3

Flunisolide

Nisolid

B3

Fluticasone

Fluspiral, Flixotide, Fixonase

B3

Triamcinolone

Nasacort

B3

Antisettici

2,4-diclorobenzil alcool +
amilmetacresolo

Benagol

A3

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