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Farmaci in Gravidanza e Allattamento

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Antidiuretici: utilizzati nella terapia delle varici esofagee (iniezione intravascolare), enuresi notturna e diabete insipido causato da un’alterazione della produzione (etiologia centrale) o dei meccanismi di funzionamento renale (etiologia nefrogena) dell’ormone ADH (ormone antidiuretico secreto dai nuclei paraventricolare e sopraottici ipotalamici e trasportata dai neuroassoni ipotalamici all’ipofisi posteriore e dalla neuroipofisi secreta nel circolo ematico), chiamato anche “vasopressina”. Viene sintetizzata in laboratorio o estratta dalla neuroipofisi suina. E’ un vasocostrittore; la sua utilizzazione in gravidanza è consentita sotto assiduo controllo clinico ed ecografico con particolare attenzione alla flussimetria uterina, placentare e fetale. Non si hanno dati certi sull’uso continuativo in allattamento.

Tab. 22 bis – Antidiuretici

Managemnt

Desmopressina

Minirin DDAVP cpr sublinguali, Desmopressina spray nasale

B3

Lipressina

Lysin vasopressina

B3

Vasopressina

Pitressin. Venlafaxina, Efexor

B3

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