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Farmaci antitubercolari: i pochi studi pubblicati per l’utilizzao dei farmaci anti-TBC in gravidanza riportano gravi danni fetali e neonatali soprattutto a carico del SNC con ritardo mentale e psicomotorio, Sono tutti da collocare in classe C-D FDA.
|
Tab. 12 – FARMACI ANTI-TBC |
MANAGEMENT |
|
|
Isoniazide |
Isoniazide, Nicozid cpr, fl |
In gravidanza: solo in caso di effettiva nevrite periferica per carenza farmaco epatotossicità |
|
Etambutolo |
Etapiam cpr, fl |
In gravidanza solo in caso di necessità |
|
Pirazinamide |
Piraldina cpr |
ipertransaminasemia, ittero, atrofia Non testata in gravidanza |
|
Rifabutina |
Mycobutin |
Solo in caso di effettiva necessità |
|
Dapsone (Disulfone) |
Utilizzato soprattutto per la terapia della |
Solo in caso di effettiva necessità |
|
Rifampicina |
Rifadin |
Sanguinamento nei neonati da inibizione della |
|
Rifampicina + Pirazinamide + Etambutolo + |
Rimstar |
Ctg D |
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